Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14866186 | 0.94 | GPR119 (0.40) | GPR119LRRK2 | |
| SCHEMBL14870764 | 0.88 | GPR119 (0.41) | GPR119 | |
| SCHEMBL14866152 | 0.84 | GPR119 (0.42) | GPR119 | |
| SCHEMBL14866396 | 0.84 | LRRK2 (0.32) | GPR119LRRK2 | |
| SCHEMBL14866308 | 0.81 | GPR119 (0.46) | GPR119 | |
| SCHEMBL14866167 | 0.80 | GPR119 (0.56) | GPR119 | |
| SCHEMBL14866314 | 0.78 | GPR119 (0.40) | GPR119 | |
| SCHEMBL14866070 | 0.78 | GPR119 (0.41) | GPR119 | |
| SCHEMBL14866289 | 0.77 | GPR119 (0.45) | GPR119 | |
| SCHEMBL14870765 | 0.76 | GPR119 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096141-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096141-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | GPR119, GCGR, GPR139 | GPR119 1/4885LRRK2 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.