Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868102 | 0.93 | KDM4E (0.42) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL17874518 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12071444 | 0.84 | ADORA2B (0.49) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12073550 | 0.83 | PDE10A (0.48) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12073553 | 0.83 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12073545 | 0.83 | KMT2A (0.50) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12073112 | 0.83 | KDM4E (0.44) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12071648 | 0.82 | ADORA2B (0.48) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12071404 | 0.81 | ADORA2B (0.47) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL12071458 | 0.81 | ADORA2B (0.50) | SMN1; SMN2NPC1RAB9AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-08 | — | — | US | disclosed |
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-08 | — | — | US | disclosed |
| US-20130092922-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
| US-20130092922-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | SCO2, AOC2, HCN2 | SMN1; SMN2 4065/4885NPC1 2473/4885RAB9A 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.