SCHEMBL14870490

SCHEMBL14870490

CC1(C)CCCC2=C1CCC(=O)C2

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ MCL1 Q07820 1/20 0.33
▸ LMNA P02545 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10316754 0.79 POLB (0.41) POLBALDH1A1TDP1MCL1CYP1A2
SCHEMBL15865874 0.74 POLB (0.41) POLBALDH1A1TDP1MCL1CYP1A2
SCHEMBL14879723 0.70 POLB (0.40) POLBALDH1A1TDP1MCL1CYP1A2
SCHEMBL30536564 0.67 ALDH1A1 (0.39) POLBALDH1A1TDP1MCL1
SCHEMBL104614 0.66 — —
SCHEMBL10894987 0.66 TRIM24 (0.42) ALDH1A1
SCHEMBL9716444 0.64 POLB (0.39) POLBALDH1A1TDP1MCL1
SCHEMBL20608593 0.64 ALDH1A1 (0.40) POLBALDH1A1TDP1MCL1LMNA
SCHEMBL14879721 0.64 ALDH1A1 (0.40) POLBALDH1A1TDP1MCL1LMNA
SCHEMBL30379423 0.63 POLB (0.45) POLBALDH1A1TDP1MCL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8658806-B2 Process for preparing optically active antrocin DEYEW BIOTECH CORP. (TW) 2014-02-25 — — US disclosed
US-8658806-B2 Process for preparing optically active antrocin DEYEW BIOTECH CORP. (TW) 2014-02-25 — — US disclosed
US-20130096324-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE ANTROCIN DEYEW BIOTECH CORP. (TW) 2013-04-18 — — US disclosed
US-20130096324-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE ANTROCIN DEYEW BIOTECH CORP. (TW) 2013-04-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096324-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE ANTROCIN KTN1, TMSB10, TSN POLB 3914/4885ALDH1A1 3568/4885TDP1 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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