SCHEMBL15865874

SCHEMBL15865874

CC1(C)CCCC2=C1CCCC2

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ MCL1 Q07820 1/20 0.34
▸ APOBEC3A P31941 1/20 0.32
▸ APOBEC3G Q9HC16 1/20 0.32
▸ SLC2A1 P11166 1/20 0.32
▸ GAA P10253 1/20 0.31
▸ ALOX12 P18054 1/20 0.31
▸ AGTR1 P30556 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10316754 0.89 POLB (0.41) POLBALDH1A1TDP1MCL1SLC2A1
SCHEMBL10753814 0.79 POLB (0.32) POLBALDH1A1TDP1
SCHEMBL30536564 0.75 ALDH1A1 (0.39) POLBALDH1A1TDP1MCL1
SCHEMBL14870490 0.74 POLB (0.43) POLBALDH1A1TDP1MCL1CYP1A2
SCHEMBL3240790 0.74 POLB (0.36) POLBALDH1A1TDP1MCL1
SCHEMBL21328389 0.73 POLB (0.32) POLBALDH1A1TDP1
SCHEMBL14879721 0.72 ALDH1A1 (0.40) POLBALDH1A1TDP1MCL1GAA
SCHEMBL18834394 0.71 ALDH1A1 (0.46) POLBALDH1A1TDP1MCL1SLC2A1
SCHEMBL31675176 0.69 POLB (0.56) POLBALDH1A1TDP1MCL1SLC2A1
SCHEMBL869519 0.69 POLB (0.56) POLBALDH1A1TDP1MCL1SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4338761-A1 PERFUMING COMPOSITIONS Firmenich SA (CH) 2024-03-20 — — EP disclosed
US-11744785-B2 Use of volatile compositions to limit or eliminate the perception of malodor FIRMENICH SA (CH) 2023-09-05 — — US disclosed
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2023-07-27 — — US disclosed
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2020-11-05 — — US disclosed
US-20190241832-A1 Improvements in or Relating to Organic Compounds GIVAUDAN SA (CH) 2019-08-08 — — US disclosed
EP-3310893-A1 IMPROVEMENTS IN OR RELATING TO ENCAPSULATED PERFUME COMPOSITIONS Givaudan SA (CH) 2018-04-25 — — EP disclosed
WO-2016207179-A1 IMPROVEMENTS IN OR RELATING TO ENCAPSULATED PERFUME COMPOSITIONS GIVAUDAN SA (CH) 2016-12-29 — — WO disclosed
US-8772348-B2 Materials and methods for pest control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744785-B2 Use of volatile compositions to limit or eliminate the perception of malodor TAS2R8, TRPA1, TAS2R10 POLB 1959/4885ALDH1A1 831/4885TDP1 4384/4885
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 POLB 1959/4885ALDH1A1 831/4885TDP1 4384/4885
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 POLB 1959/4885ALDH1A1 831/4885TDP1 4384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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