Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648553 | 0.90 | GAA (0.47) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL11034177 | 0.79 | HDAC8 (0.65) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL1454495 | 0.78 | MEN1 (0.63) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL392625 | 0.78 | ALDH1A1 (0.82) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL425873 | 0.76 | HDAC8 (0.61) | MEN1KMT2AHDAC8HDAC6GAA | |
| Phenaceturic Acid SCHEMBL196523 | 0.76 | ATM (0.62) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL10585628 | 0.76 | TRPV1 (0.83) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL22559999 | 0.76 | MEN1 (0.61) | MEN1KMT2AHDAC8HDAC6GAA | |
| SCHEMBL1095091 | 0.76 | MEN1 (0.61) | MEN1KMT2AHDAC8HDAC6GAA | |
| Phenaceturic Acid SCHEMBL14126285 | 0.76 | ATM (0.62) | MEN1KMT2AHDAC8HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315861-A1 | BETA-LACTAMASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-23 | — | — | US | disclosed |
| WO-2013056163-A1 | BETA-LACTAMASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315861-A1 | BETA-LACTAMASE INHIBITORS | BTD, GUSB, BLVRB | MEN1 2814/4885KMT2A 1710/4885HDAC8 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.