Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980997 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14873822 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23612575 | 0.74 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10016076 | 0.74 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14495731 | 0.74 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24120969 | 0.74 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10195112 | 0.74 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19325256 | 0.74 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24506182 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21716641 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596805-A1 | Prodrug comprising a drug linker conjugate | Ascendis Pharma A/S (DK) | 2013-05-29 | — | — | EP | disclosed |
| WO-2013053856-A1 | PREVENTION AND TREATMENT OF OCULAR CONDITIONS | ASCENDIS PHARMA A/S (DK) | 2013-04-18 | — | — | WO | disclosed |