Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874517 | 0.85 | MEN1 (0.46) | HTTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL14874548 | 0.83 | HTT (0.44) | HTTL3MBTL1PPARDPPARAPPARG | |
| SCHEMBL14874594 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14874678 | 0.80 | ALDH1A1 (0.35) | HTTMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL14874527 | 0.78 | PPARG (0.37) | HTTMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL747405 | 0.77 | TSHR (0.51) | HTTMEN1KMT2APPARGALDH1A1 | |
| SCHEMBL14874417 | 0.77 | CYP4F2 (0.47) | HTTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL14874575 | 0.77 | MEN1 (0.33) | HTTMEN1KMT2APPARG | |
| SCHEMBL2436464 | 0.77 | ALOX15 (0.49) | PPARDPPARAPPARGALDH1A1TSHR | |
| SCHEMBL7854190 | 0.76 | KMT2A (0.47) | HTTMEN1KMT2AATMPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768873-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-11-22 | — | — | EP | disclosed |
| US-8921253-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-12-30 | — | — | US | disclosed |
| US-20140243490-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2014-08-28 | — | — | US | disclosed |
| EP-2768873-A2 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013057026-A2 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2013-04-25 | — | — | WO | disclosed |
| EP-2583985-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2013-04-24 | — | — | EP | disclosed |