Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874461 | 0.88 | ITGA4 (0.45) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874565 | 0.86 | ITGA4 (0.42) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874582 | 0.85 | ITGA4 (0.43) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874564 | 0.85 | GAA (0.40) | POLBHTTNPSR1L3MBTL1GAA | |
| SCHEMBL14874624 | 0.84 | ITGA4 (0.45) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874674 | 0.84 | ITGA4 (0.40) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874456 | 0.82 | ITGA4 (0.41) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874356 | 0.82 | GAA (0.44) | MMP8POLBHTTNPSR1L3MBTL1 | |
| SCHEMBL14874555 | 0.81 | CA1 (0.42) | ITGA4ITGB7MMP8CYP2D6CYP2C19 | |
| SCHEMBL14874634 | 0.79 | CA1 (0.40) | ITGA4ITGB7MMP8CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768873-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-11-22 | — | — | EP | disclosed |
| US-8921253-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-12-30 | — | — | US | disclosed |
| US-20140243490-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2014-08-28 | — | — | US | disclosed |
| EP-2583985-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2013-04-24 | — | — | EP | disclosed |