SCHEMBL14874564

SCHEMBL14874564

CCCC(c1ccccc1OC)C(C)(C(=O)OCC)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ TAS1R3 Q7RTX0 2/20 0.40
▸ TAS1R1 Q7RTX1 2/20 0.40
▸ POLB P06746 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ PLIN1 O60240 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ PLIN5 Q00G26 1/20 0.39
▸ ABHD5 Q8WTS1 1/20 0.39
▸ TSHR P16473 2/20 0.39
▸ HTT P42858 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ PIN1 Q13526 1/20 0.37
▸ CTSS P25774 1/20 0.36
▸ CTSK P43235 1/20 0.36
▸ PRSS1 P07477 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874353 0.88 POLB (0.42) GAAKDM4ETAS1R3TAS1R1POLB
SCHEMBL14874677 0.85 ITGA4 (0.43) GAAPOLBMAPTMEN1KMT2A
SCHEMBL14874479 0.85 PIN1 (0.38) GAAKDM4ETAS1R3TAS1R1POLB
SCHEMBL14874404 0.85 POLB (0.42) GAAKDM4ETAS1R3TAS1R1POLB
SCHEMBL14874454 0.85 POLB (0.39) GAAKDM4ETAS1R3TAS1R1POLB
SCHEMBL14874356 0.84 GAA (0.44) GAAKDM4EPOLBMAPTMEN1
SCHEMBL14874432 0.83 TSHR (0.39) GAAKDM4ETAS1R3TAS1R1POLB
SCHEMBL14874508 0.81 TSHR (0.39) GAAKDM4ETAS1R3TAS1R1POLB
SCHEMBL14874357 0.81 GAA (0.41) GAAKDM4EPOLBMAPTMEN1
SCHEMBL14874488 0.80 TSHR (0.40) GAAKDM4ETAS1R3TAS1R1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 — — EP disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 — — US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 — — US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 — — EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 — — WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 — — EP disclosed
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