Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CPS1 | P31327 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1529119 | 0.91 | SNCA (0.41) | SNCAEGFRUCHL1CYP1A1CYP1A2 | |
| SCHEMBL586551 | 0.85 | CXCR2 (0.39) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL18117618 | 0.82 | SNCA (0.41) | SNCAUCHL1CYP1A2LPLLIPG | |
| SCHEMBL15573245 | 0.81 | ALK (0.32) | — | |
| SCHEMBL15572934 | 0.81 | PTGS1 (0.38) | — | |
| SCHEMBL14689746 | 0.79 | SNCA (0.41) | SNCAEGFRUCHL1CYP1A1CYP1A2 | |
| SCHEMBL276828 | 0.78 | EGFR (0.48) | EGFRKDRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29785358 | 0.78 | EGFR (0.48) | EGFRKDRCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL22095433 | 0.76 | LPL (0.40) | EGFRLPLLIPG | |
| SCHEMBL24873949 | 0.75 | LPL (0.35) | EGFRUCHL1LPLLIPGCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029560-B1 | 1,3-OXAZOLIDIN-2-ONE DERIVATIVES USEEFUL AS CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2013-04-24 | — | — | EP | disclosed |