SCHEMBL1487474

SCHEMBL1487474

CC(=O)Nc1ccc(O[C]=O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
SMN1; SMN2 Q16637 5/20 0.55
HTT P42858 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ALDH1A1 P00352 5/20 0.55
KDM4E B2RXH2 1/20 0.55
HPGD P15428 1/20 0.55
CYP2C19 P33261 1/20 0.55
RAB9A P51151 1/20 0.55
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MAPT P10636 3/20 0.53
CA12 O43570 1/20 0.53
BRD4 O60885 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11858501 0.83 KMT2A (0.61) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL7461810 0.83 KMT2A (0.61) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL7348164 0.80 KMT2A (0.53) MEN1KMT2ALMNACYP1A2SMN1; SMN2
SCHEMBL6516221 0.79 KMT2A (0.73) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL7350322 0.79 MTNR1A (0.55) MEN1KMT2ATDP1CYP1A2SMN1; SMN2
SCHEMBL861674 0.78 SMN1; SMN2 (0.84) MEN1KMT2ATDP1SMN1; SMN2HTT
SCHEMBL14808444 0.78 KMT2A (1.00) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL171415 0.78 SMN1; SMN2 (0.73) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL27267778 0.78 SMN1; SMN2 (0.73) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL8374496 0.78 CYP17A1 (0.48) CYP1A2SMN1; SMN2HPGDCYP2C19RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999052936-A2 ARGININE PEPTIDE ANALOGS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS EISAI CO., LTD. (JP) 1999-10-21 WO claimed
WO-2024070633-A1 OPTICAL FILM, POLARIZING PLATE, COMPOSITION FOR FORMING ALIGNMENT FILM, AND METHOD FOR PRODUCING POLARIZING PLATE 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2024070463-A1 POLYMER AND COMPOSITION 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2024070641-A1 OPTICAL FILM, POLARIZING PLATE, COMPOSITION FOR ALIGNMENT FILM FORMATION, AND METHOD FOR PRODUCING POLARIZING PLATE 富士フイルム株式会社 2024-04-04 WO disclosed
EP-2301519-A1 Ultraviolet absorbing composition Fujifilm Corporation (JP) 2011-03-30 EP disclosed
US-20110059033-A1 ULTRAVIOLET ABSORBING COMPOSITION FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
US-6613313-B2 Aniline compound-containing hair dye composition and method of dyeing hair FUJI PHOTO FILM CO., LTD. (JP) 2003-09-02 US disclosed
US-20020197223-A1 ANILINE COMPOUND CONTAINING HAIR DYE COMPOSITION AND METHOD OF DYEING HAIR FUJIFILM CORPORATION (JP) 2002-12-26 US disclosed
US-6489086-B1 Silver halide color photographic photosensitive material and method for forming image FUJI PHOTO FILM CO., LTD. (JP) 2002-12-03 US disclosed
US-6258518-B1 AN AROMATIC OXY, NITRILE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2001-07-10 US disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
EP-0276124-B1 PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE Sankyo Company Limited (JP) 1992-05-20 EP disclosed
US-4981872-A ANTIULCER SANKYO COMPANY LIMITED (JP) 1991-01-01 US disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0276124-A2 Prostaglandin derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1988-07-27 EP disclosed
US-4367272-A MORDANTS, REFLECTION FUJI PHOTO FILM CO., LTD (JP) 1983-01-04 US disclosed
US-4268621-A Direct positive photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 US disclosed
US-4264495-A EXHIBITING GOOD COLOFASTNESS AND DYEABILITY ON POLYAMIDES AND OTHER FIBERS EASTMAN KODAK COMPANY (US) 1981-04-28 US disclosed
US-4247458-A COUPLING DIAZONIUM SALT WITH DISPERSE DYE COUPLER WITH DISPLACEABLE GROUP OTHER THAN HYDROGEN EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4070352-A COLORFAST, SUBLIMATION AND OZONE RESISTANT BLUE AZO DYES FOR POLYAMIDES EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059033-A1 ULTRAVIOLET ABSORBING COMPOSITION C1S, F12, TYR MEN1 321/4885KMT2A 2604/4885TDP1 3062/4885
US-20020197223-A1 ANILINE COMPOUND CONTAINING HAIR DYE COMPOSITION AND METHOD OF DYEING HAIR TYR, DAO, HAAO MEN1 2722/4885KMT2A 1959/4885TDP1 1854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.