Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571811 | 0.94 | MTNR1A (0.71) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14384396 | 0.94 | MTNR1A (0.76) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3468387 | 0.91 | MAPT (0.68) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6814406 | 0.91 | CYP1A2 (0.69) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11481934 | 0.91 | IDO1 (0.66) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18409069 | 0.89 | NPC1 (0.67) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10926166 | 0.89 | NPC1 (0.59) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13728829 | 0.88 | IDO1 (0.71) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10923463 | 0.86 | IDO1 (0.57) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3185469 | 0.86 | MEN1 (0.63) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1686 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650912-B | 2-Mercapto-6-methoxyquinoline-3-formaldehyde-N-oxide and synthetic method and application thereof | 灌南森迪门业有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118344264-A | 13Purification method of C Mexaxetine13C Meishasistine | 北京华亘安邦科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| US-20240207453-A1 | 13C METHACETIN GRANULE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING RICHEN-FORCE SCIENCE & TECHNOLOGY CO., LTD (CN) | 2024-06-27 | — | — | US | claimed |
| CN-114681446-B | Application of acetamide compound as glutamate dehydrogenase inhibitor | 南京盛德生物科技研究院有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117772103-A | Preparation device and preparation method of 3-nitro-4-methoxy acetanilide | 杭州吉华江东化工有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117777029-A | Production method of omeprazole pharmaceutical intermediate 2-mercapto-5-methoxybenzimidazole | 上海卓鼎生物技术有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-4327805-A1 | 13C METHACETIN GRANULE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Richen-Force Science & Technology Co., Ltd (CN) | 2024-02-28 | — | — | EP | claimed |
| CN-115583894-B | Method and device for continuously producing 2-nitro-4-methoxy acetanilide | 浙江迪邦化工有限公司 | 2024-02-27 | — | — | CN | claimed |
| US-20230282357-A1 | ACUTE LIVER PATIENT MANAGEMENT | Meridian Bioscience Israel Ltd. (IL) | 2023-09-07 | — | — | US | claimed |
| CN-116688160-A | The method comprises the following steps of 13 C-mexacetin orally disintegrating tablet as well as preparation method and application thereof | 北京华亘安邦科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | PHARMACIA & UPJOHN COMPANY | 2002-08-08 | — | — | US | claimed |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2002-06-20 | — | — | US | claimed |
| WO-2002024701-A2 | SUBSTITUTED AZEPINO[4,5B)INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024700-A2 | SUBSTITUTED AZEPINO[4,5b]INDOLINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | claimed |
| EP-0913161-A2 | Diagnostic agent for diabetes | Tokyo Gas Co., Ltd. (JP) | 1999-05-06 | — | — | EP | claimed |
| EP-0701558-A1 | PROCESS OF MAKING SPIROCYCLES AND ANALOGS THEREOF | MERCK & CO. INC. (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1994029317-A1 | PROCESS OF MAKING SPIROCYCLES AND ANALOGS THEREOF | MERCK & CO., INC. (US) | 1994-12-22 | — | — | WO | claimed |
| US-4285863-A | YELLOW-TO-RED ORGANIC PIGMENTS; PLASTICS AND FABRICS; PAINTS, ENAMELS, AND INKS | MONTEDISON S.P.A. (IT) | 1981-08-25 | — | — | US | claimed |
| US-4139558-A | Process for preparing free-flowing 2-nitro-4-acetylamino-anisole | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | claimed |
| US-3952129-A | AROMATIC SECONDARY AMINE | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | HTR5A, HTR1A, HTR1E | SMN1; SMN2 1296/4885NPC1 1345/4885RAB9A 698/4885 |
| US-20240207453-A1 | 13C METHACETIN GRANULE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | GOT2, GOT1, CYP4F11 | SMN1; SMN2 3310/4885NPC1 1781/4885RAB9A 1420/4885 |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | HTR5A, HTR1A, HTR4 | SMN1; SMN2 1106/4885NPC1 1176/4885RAB9A 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.