Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488622 | 0.89 | GPR119 (0.75) | GPR119ALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL14874928 | 0.86 | GPR119 (0.79) | GPR119POLBMAPTMEN1KMT2A | |
| SCHEMBL14874905 | 0.85 | GPR119 (0.53) | GPR119POLBADRB2MAPTSMN1; SMN2 | |
| SCHEMBL14874871 | 0.83 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14874908 | 0.82 | GPR119 (0.75) | GPR119POLBMAPTMEN1KMT2A | |
| SCHEMBL14874967 | 0.82 | GPR119 (0.63) | GPR119 | |
| SCHEMBL14874841 | 0.81 | GPR119 (0.62) | GPR119 | |
| SCHEMBL14874833 | 0.80 | GPR119 (0.40) | GPR119MAPT | |
| SCHEMBL14874865 | 0.80 | GPR119 (0.60) | GPR119 | |
| SCHEMBL27870728 | 0.79 | GPR119 (0.78) | GPR119POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111107-B1 | HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS | METABOLEX INC (US) | 2013-04-24 | — | — | EP | claimed |