SCHEMBL1487562

SCHEMBL1487562

CC(C)(c1ccccc1)c1cc(-c2nc3ccccc3s2)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.48
KDM4E B2RXH2 9/20 0.48
RAB9A P51151 8/20 0.48
NPC1 O15118 6/20 0.48
NPSR1 Q6W5P4 2/20 0.48
SMN1; SMN2 Q16637 7/20 0.46
ALDH1A1 P00352 7/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
GAA P10253 5/20 0.45
POLB P06746 3/20 0.45
HSD17B10 Q99714 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
APP P05067 1/20 0.45
THRB P10828 1/20 0.45
ALOX15 P16050 1/20 0.45
CASP1 P29466 1/20 0.45
SNCA P37840 1/20 0.45
CASP7 P55210 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8250064 0.89 MAPT (0.43) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL2774898 0.84 TNF (0.55) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL2184065 0.80 MAPT (0.47) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL22320286 0.74 ESR1 (0.39) ALDH1A1HSD17B10TDP1ALOX15CASP1
SCHEMBL30422802 0.74 ESR1 (0.39) ALDH1A1HSD17B10TDP1ALOX15CASP1
SCHEMBL5706284 0.74 CNR1 (0.48) ALDH1A1HSD17B10TDP1ALOX15CASP1
SCHEMBL1276281 0.73 ESR1 (0.57) ALDH1A1HSD17B10TDP1ALOX15CASP1
SCHEMBL34465504 0.73 MAPT (0.64) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL7059138 0.73 MAPT (0.64) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL17265013 0.71 MAPT (0.67) MAPTKDM4ERAB9ANPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360353-A2 Plate of material with polymeric structure, resistant to sun light LA/ES LAMINATI ESTRUSI TERMOPLASTICI S.P.A. (IT) 1990-03-28 EP claimed
EP-3498720-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF PMC Organometallix, Inc. (US) 2019-06-19 EP disclosed
EP-2300487-B1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF PMC ORGANOMETALLIX INC (US) 2019-03-13 EP disclosed
US-8198352-B2 High purity monoalkyltin compounds and uses thereof ARKEMA FRANCE (FR) 2012-06-12 US disclosed
US-20110166268-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF ARKEMA FRANCE (FR) 2011-07-07 US disclosed
EP-2300487-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF ARKEMA FRANCE (FR) 2011-03-30 EP disclosed
EP-2123659-A1 High purity monoalkyltin compounds and uses thereof ARKEMA FRANCE (FR) 2009-11-25 EP disclosed
WO-2009138474-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF ARKEMA FRANCE (FR) 2009-11-19 WO disclosed
EP-1465943-A2 FLAME RETARDANT CONPOSITIONS Ciba SC Holding AG (CH) 2004-10-13 EP disclosed
WO-2003050175-A2 FLAME RETARDANT CONPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-19 WO disclosed
EP-0360353-A2 Plate of material with polymeric structure, resistant to sun light LA/ES LAMINATI ESTRUSI TERMOPLASTICI S.P.A. (IT) 1990-03-28 EP disclosed