Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487562 | 0.89 | MAPT (0.48) | MAPTRAB9ANPC1KDM4ENPSR1 | |
| SCHEMBL6695599 | 0.84 | MAPT (0.45) | MAPTRAB9ANPC1KDM4ENPSR1 | |
| SCHEMBL2184065 | 0.81 | MAPT (0.47) | MAPTRAB9ANPC1KDM4ENPSR1 | |
| SCHEMBL29948293 | 0.80 | MAPT (0.57) | MAPTRAB9ANPC1KDM4ENPSR1 | |
| SCHEMBL3982225 | 0.80 | MAPT (0.57) | MAPTRAB9ANPC1KDM4ENPSR1 | |
| SCHEMBL2774898 | 0.78 | TNF (0.55) | MAPTRAB9ANPC1KDM4ENPSR1 | |
| SCHEMBL28041166 | 0.77 | SHBG (0.46) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1743018 | 0.72 | SHBG (0.31) | — | |
| SCHEMBL76991 | 0.72 | NPC1 (0.40) | MAPTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL29353178 | 0.72 | NPC1 (0.40) | MAPTRAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984958-A1 | BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054173-A1 | BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-12-03 | — | — | WO | disclosed |