SCHEMBL2184065

SCHEMBL2184065

CCC(C)(C)c1cc(-c2nc3ccccc3s2)c(O)c(C(C)(C)CC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.47
KDM4E B2RXH2 9/20 0.47
RAB9A P51151 8/20 0.47
NPC1 O15118 7/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KMT2A Q03164 6/20 0.45
ALDH1A1 P00352 6/20 0.45
MEN1 O00255 5/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
GAA P10253 5/20 0.44
POLB P06746 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HSD17B10 Q99714 2/20 0.44
THRB P10828 2/20 0.44
APP P05067 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 1/20 0.44
SNCA P37840 1/20 0.44
CASP7 P55210 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2774898 0.83 TNF (0.55) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL8250064 0.81 MAPT (0.43) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL1487562 0.80 MAPT (0.48) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL6695599 0.77 MAPT (0.45) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL19135205 0.75 TNF (0.45) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL22320301 0.75 MAPK1 (0.40) RAB9ANPC1NPSR1KMT2AALDH1A1
SCHEMBL7189472 0.74 SMN1; SMN2 (0.40) MAPTRAB9ANPC1NPSR1KMT2A
SCHEMBL28069366 0.74 MAPK1 (0.43) MAPTRAB9ANPC1NPSR1KMT2A
SCHEMBL7059072 0.74 TNF (0.47) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL3982225 0.72 MAPT (0.57) MAPTKDM4ERAB9ANPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498720-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF PMC Organometallix, Inc. (US) 2019-06-19 EP disclosed
EP-2300487-B1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF PMC ORGANOMETALLIX INC (US) 2019-03-13 EP disclosed
US-8198352-B2 High purity monoalkyltin compounds and uses thereof ARKEMA FRANCE (FR) 2012-06-12 US disclosed
US-20110166268-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF ARKEMA FRANCE (FR) 2011-07-07 US disclosed
EP-2150582-A1 COMPOSITION WITH INCREASED STRESS CRACKING RESISTANCE Evonik Röhm GmbH (DE) 2010-02-10 EP disclosed
EP-2123659-A1 High purity monoalkyltin compounds and uses thereof ARKEMA FRANCE (FR) 2009-11-25 EP disclosed
WO-2008148595-A1 COMPOSITION WITH INCREASED STRESS CRACKING RESISTANCE EVONIK RÖHM GMBH (DE) 2008-12-11 WO disclosed
EP-0175473-B1 ABRASION RESISTANT COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-20 EP disclosed
EP-0127813-B1 WATER-REPELLENT RESISTANT, ABRASION RESISTANT COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-06 EP disclosed
US-4619949-A ODORLESS, WATERPROOF, COPOLYMERIZED EPOXYTERMINATED SILANES AND AN ALIPHATIC MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-10-28 US disclosed
US-4587169-A EPOXY-TERMINATED SILANE AND EPOXY RESIN MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-05-06 US disclosed
EP-0175473-A2 Abrasion resistant coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-03-26 EP disclosed
US-4497861-A COPOLYMER OF EPOXY SILANE AND LIMONENE MONOXIDE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-02-05 US disclosed
EP-0127813-A1 Water-repellent resistant, abrasion resistant coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-12-12 EP disclosed
US-4168332-A Non-glare glass coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-09-18 US disclosed
US-4156046-A POLYEPOXIDES, EPOXY-TERMINATED SILANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-05-22 US disclosed