SCHEMBL1487642

SCHEMBL1487642

O=Cc1ccc2c(C=O)ccc(C=O)c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
ALDH1A1 P00352 7/20 0.43
MEN1 O00255 3/20 0.43
POLB P06746 3/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PTGS2 P35354 1/20 0.43
KIF11 P52732 2/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
IP6K1 Q92551 1/20 0.41
HPGD P15428 1/20 0.41
PTK2B Q14289 1/20 0.41
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
TSHR P16473 1/20 0.39
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27768942 0.79 MEN1 (0.47) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL29485028 0.77 ALDH1A1 (0.48) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL1489425 0.77 ALDH1A1 (0.48) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL9883875 0.74 KIF11 (0.42) KDM4EALDH1A1MEN1POLBKMT2A
SCHEMBL1666511 0.74 KIF11 (0.42) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL3774265 0.73 KIF11 (0.59) KDM4EALDH1A1MEN1POLBKMT2A
SCHEMBL19186626 0.73 KIF11 (0.59) KDM4EALDH1A1MEN1POLBKMT2A
SCHEMBL3447841 0.73 ERN1 (0.42) KDM4EALDH1A1MEN1POLBKMT2A
SCHEMBL29956305 0.73 CYP2A6 (0.66) KDM4EALDH1A1KIF11MAPTCYP2A6
SCHEMBL28880208 0.73 CYP2A6 (0.40) KDM4EALDH1A1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180171110-A1 TERMINAL-MODIFIED CONJUGATED DIENE-VINYL AROMATIC HYDROCARBON COPOLYMER AND SYNTHESIS METHOD THEREOF, RUBBER COMPOSITION AND TIRE CHI MEI CORPORATION (TW) 2018-06-21 US disclosed
US-9187644-B2 Continuous processing of asphalt formulations BUILDING MATERIALS INVESTMENT CORPORATION (US) 2015-11-17 US disclosed
US-9145494-B2 Rubber composition including a phenolic resin MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2015-09-29 US disclosed
US-20140275337-A1 CONTINUOUS PROCESSING OF ASPHALT FORMULATIONS BUILDING MATERIALS INVESTMENT CORPORATION (US) 2014-09-18 US disclosed
EP-2478047-B1 RUBBER COMPOSITION COMPRISING A PHENOLIC RESIN MICHELIN & CIE (FR) 2013-07-31 EP disclosed
US-20120283372-A1 Rubber Composition Including a Phenolic Resin COMPAGNIE GÉNÉRALE DES ETABLISSEMENTS MICHELIN (FR) 2012-11-08 US disclosed
EP-1316582-B1 POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES KURARAY CO (JP) 2012-10-31 EP disclosed
EP-2478047-A1 RUBBER COMPOSITION INCLUDING A PHENOLIC RESIN Société de Technologie MICHELIN (FR) 2012-07-25 EP disclosed
WO-2011029938-A1 RUBBER COMPOSITION INCLUDING A PHENOLIC RESIN SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-03-17 WO disclosed
US-7820261-B2 Polyvinyl alcohol resin composition and multilayer packages KURARAY CO., LTD. (JP) 2010-10-26 US disclosed
US-4168341-A Fabric-backed teleblock copolymer composition with dulled surface useful in footwear uppers PHILLIPS PETROLEUM CO. (US) 1979-09-18 US disclosed
US-4163764-A COUPLED ADDITION POLYMER PHILLIPS PETROLEUM COMPANY (US) 1979-08-07 US disclosed
US-4138378-A Liquid polyalkene in thermoplastic elastomer sealant formulation PHILLIPS PETROLEUM COMPANY (US) 1979-02-06 US disclosed
US-4137391-A Continuous solution polymerization of a conjugated diene with a monovinylaromatic compound using alkoxysilicon treating agents in the first reactor means of a reactor series PHILLIPS PETROLEUM COMPANY (US) 1979-01-30 US disclosed
US-4107236-A OZONE-RESISTANT THERMOPLASTIC ELASTOMERS PHILLIPS PETROLEUM COMPANY (US) 1978-08-15 US disclosed
US-4104326-A Resinous radial-linear copolymer blend having blocks with a heterogeneity index ranging from 2.5 to 4 PHILLIPS PETROLEUM COMPANY (US) 1978-08-01 US disclosed
US-4101482-A Sealant based on mixture of unsaturated and hydrogenated block copolymers PHILLIPS PETROLEUM COMPANY (US) 1978-07-18 US disclosed
US-4101484-A AROMATIC OLEFIN-CONJUGATED DIENE BLOCK POLYMER PHILLIPS PETROLEUM COMPANY (US) 1978-07-18 US disclosed
US-4091198-A Suppressing gel in the continuous solution polymerization of a conjugated diene with a monovinyl aromatic compound PHILLIPS PETROLEUM COMPANY (US) 1978-05-23 US disclosed
US-4051197-A BLEND OF RADIAL BLOCK COPOLYMERS HAVING HIGH IMPACT STRENGTH PHILLIPS PETROLEUM COMPANY (US) 1977-09-27 US disclosed