Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967630 | 0.88 | ACE (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5967612 | 0.86 | KDM4E (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5967603 | 0.85 | TLR2 (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5967596 | 0.85 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL931196 | 0.81 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5967614 | 0.80 | KMT2A (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12157363 | 0.80 | KDM4E (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5967577 | 0.79 | SIRT6 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL930076 | 0.78 | KDM4E (0.53) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5967639 | 0.78 | TLR2 (0.37) | SIRT6SIRT1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989372-B1 | Antioxidants, preparation methods and uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-01-24 | — | — | US | claimed |
| US-6979747-B2 | Antioxidants, preparation processes and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-12-27 | — | — | US | claimed |
| US-20040158092-A1 | Novel antioxidants, preparation processes and their uses | OIRY JOEL (FR) | 2004-08-12 | — | — | US | claimed |
| EP-1183237-B1 | NOVEL ANTIOXIDANTS, PREPARATION METHODS AND USES | CENTRE NAT RECH SCIENT (FR) | 2004-01-28 | — | — | EP | claimed |
| EP-1183237-A1 | NOVEL ANTIOXIDANTS, PREPARATION METHODS AND USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-03-06 | — | — | EP | claimed |
| WO-2000073266-A1 | NOVEL ANTIOXIDANTS, PREPARATION METHODS AND USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-12-07 | — | — | WO | claimed |
| US-20230277566-A1 | BROAD SPECTRUM ANTIVIRAL AND METHODS OF USE | THE BURLINGTON HC RES GROUP INC (US) | 2023-09-07 | — | — | US | disclosed |
| US-20210228601-A1 | Broad Spectrum Antiviral and Methods of Use | THE BURLINGTON HC RES GROUP INC (US) | 2021-07-29 | — | — | US | disclosed |
| US-20180344751-A1 | Broad Spectrum Antiviral and Methods of Use | THE BURLINGTON HC RES GROUP INC (US) | 2018-12-06 | — | — | US | disclosed |
| US-9849143-B2 | Broad spectrum antiviral and methods of use | THE BURLINGTON HC RESEARCH GROUP, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170157151-A1 | Broad Spectrum Antiviral and Methods of Use | THE BURLINGTON HC RES GROUP INC (US) | 2017-06-08 | — | — | US | disclosed |
| US-9585849-B2 | Broad spectrum antiviral and methods of use | THE BURLINGTON HC RESEARCH GROUP, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160374967-A1 | ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS | THE GOVERNMENT OF THE U S A AS REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) | 2016-12-29 | — | — | US | disclosed |
| US-20090239817-A1 | ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS | GOVERMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT OF HEALTH (US) | 2009-09-24 | — | — | US | disclosed |
| EP-2010166-A2 | ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007123868-A2 | ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-11-01 | — | — | WO | disclosed |
| US-6989372-B1 | Antioxidants, preparation methods and uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-01-24 | — | — | US | disclosed |
| US-6979747-B2 | Antioxidants, preparation processes and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-12-27 | — | — | US | disclosed |
| US-20040158092-A1 | Novel antioxidants, preparation processes and their uses | OIRY JOEL (FR) | 2004-08-12 | — | — | US | disclosed |
| EP-1183237-B1 | NOVEL ANTIOXIDANTS, PREPARATION METHODS AND USES | CENTRE NAT RECH SCIENT (FR) | 2004-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228601-A1 | Broad Spectrum Antiviral and Methods of Use | MAVS, EIF2AK2, ZC3HAV1 | KDM4E 4561/4885MAPT 2984/4885THRB 4374/4885 |
| US-20040158092-A1 | Novel antioxidants, preparation processes and their uses | GPX1, ACOX1, NAT1 | KDM4E 4452/4885MAPT 3015/4885THRB 680/4885 |
| US-20180344751-A1 | Broad Spectrum Antiviral and Methods of Use | MAVS, EIF2AK2, ZC3HAV1 | KDM4E 4561/4885MAPT 2984/4885THRB 4374/4885 |
| US-20160374967-A1 | ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS | TYMP, MTAP, TPMT | KDM4E 4434/4885MAPT 2773/4885THRB 1728/4885 |
| US-20170157151-A1 | Broad Spectrum Antiviral and Methods of Use | MAVS, EIF2AK2, ZC3HAV1 | KDM4E 4561/4885MAPT 2984/4885THRB 4374/4885 |
| US-20090239817-A1 | ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS | TYMP, MTAP, TPMT | KDM4E 4434/4885MAPT 2773/4885THRB 1728/4885 |
| US-20230277566-A1 | BROAD SPECTRUM ANTIVIRAL AND METHODS OF USE | MAVS, EIF2AK2, ZC3HAV1 | KDM4E 4561/4885MAPT 2984/4885THRB 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.