SCHEMBL14876573

SCHEMBL14876573

C[N+](C)(C)CCNc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.57
▸ EGFR P00533 3/20 0.57
▸ MAPK1 P28482 3/20 0.57
▸ L3MBTL1 Q9Y468 3/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ RAB9A P51151 2/20 0.57
▸ TDP1 Q9NUW8 2/20 0.57
▸ PABPC1 P11940 1/20 0.57
▸ MEN1 O00255 4/20 0.56
▸ KMT2A Q03164 4/20 0.56
▸ POLB P06746 3/20 0.56
▸ ALDH1A1 P00352 3/20 0.56
▸ BLM P54132 2/20 0.56
▸ RAD52 P43351 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ HTT P42858 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ TERT O14746 6/20 0.55
▸ MAOA P21397 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14876558 0.94 TERT (0.59) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL14876242 0.89 TERT (0.58) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
Sulfuric Acid SCHEMBL11512562 0.86 MAPT (0.58) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
Sulfuric Acid SCHEMBL11512567 0.86 MEN1 (0.55) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL25937776 0.86 NSD2 (0.58) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL14876694 0.86 TERT (0.53) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL14876751 0.85 MAPT (0.54) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL25937202 0.85 TERT (0.57) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL18087424 0.85 MAPT (0.50) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL10726314 0.84 TERT (0.53) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11255761-B2 Method of analysing a cell or other biological material containing a nucleic acid BIOSTATUS LIMITED (GB) 2022-02-22 — — US disclosed
EP-3366667-B1 METHOD OF ANALYSING A CELL OR OTHER BIOLOGICAL MATERIAL CONTAINING NUCLEIC ACID BIOSTATUS LTD (GB) 2021-02-17 — — EP disclosed
EP-2556047-B1 METHOD OF ANALYSING A CELL OR OTHER BIOLOGICAL MATERIAL CONTAINING A NUCLEIC ACID BIOSTATUS LTD (GB) 2018-06-06 — — EP disclosed
US-20150268142-A1 METHOD OF ANALYSING A CELL OR OTHER BIOLOGICAL MATERIAL CONTAINING A NUCLEIC ACID BIOSTATUS LIMITED (GB) 2015-09-24 — — US disclosed
US-9051467-B2 Method of analysing a cell or other biological material containing a nucleic acid BIOSTATUS LIMITED (GB) 2015-06-09 — — US disclosed
US-20130101994-A1 Method of Analysing a Cell or Other Biological Material Containing a Nucleic Acid BIOSTATUS LIMITED (GB) 2013-04-25 — — US disclosed
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