SCHEMBL14876751

SCHEMBL14876751

CC[N+](CC)(CC)CCNc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.54
▸ MAPK1 P28482 3/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ EGFR P00533 2/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ RAB9A P51151 2/20 0.54
▸ PABPC1 P11940 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ MEN1 O00255 4/20 0.53
▸ KMT2A Q03164 4/20 0.53
▸ POLB P06746 3/20 0.53
▸ BLM P54132 2/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ RAD52 P43351 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ RECQL P46063 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ MAOA P21397 1/20 0.49
▸ NSD2 O96028 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552095 0.96 NSD2 (0.51) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL14876259 0.94 TERT (0.50) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL14876929 0.90 MEN1 (0.55) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL14876513 0.87 NSD2 (0.47) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL9369089 0.86 MAPT (0.54) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL14876573 0.85 MAPT (0.57) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL10781791 0.83 MAPT (0.62) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL9364767 0.81 NSD2 (0.49) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL6291460 0.81 MEN1 (0.64) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1
SCHEMBL20334201 0.81 CYP1A2 (0.43) MAPTMAPK1SMN1; SMN2EGFRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11255761-B2 Method of analysing a cell or other biological material containing a nucleic acid BIOSTATUS LIMITED (GB) 2022-02-22 — — US disclosed
US-20150268142-A1 METHOD OF ANALYSING A CELL OR OTHER BIOLOGICAL MATERIAL CONTAINING A NUCLEIC ACID BIOSTATUS LIMITED (GB) 2015-09-24 — — US disclosed
US-9051467-B2 Method of analysing a cell or other biological material containing a nucleic acid BIOSTATUS LIMITED (GB) 2015-06-09 — — US disclosed
US-20130101994-A1 Method of Analysing a Cell or Other Biological Material Containing a Nucleic Acid BIOSTATUS LIMITED (GB) 2013-04-25 — — US disclosed
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