Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.41 |
| ▸ | GAPDH | P04406 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381922 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL19493436 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL19493438 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL18797894 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL8381924 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL27153067 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL31419333 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL6396836 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL21305068 | 0.84 | TYMP (0.55) | TYMPP2RY12 | |
| SCHEMBL23216815 | 0.83 | TYMP (0.45) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102652-A1 | METHODS AND COMPOSITIONS RELATED TO MODIFIED ADENOSINES FOR CONTROLLING OFF-TARGET EFFECTS IN RNA INTERFERENCE | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102652-A1 | METHODS AND COMPOSITIONS RELATED TO MODIFIED ADENOSINES FOR CONTROLLING OFF-TARGET EFFECTS IN RNA INTERFERENCE | ADAR, RNMT, NSUN2 | TYMP 589/4885GAPDH 277/4885SIRT2 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.