Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198800 | 0.84 | ANPEP (0.40) | IMPDH2IMPDH1NCOA3MEN1LMNA | |
| SCHEMBL2460593 | 0.79 | IMPDH2 (0.48) | IMPDH2IMPDH1MEN1LMNATHRB | |
| SCHEMBL31085580 | 0.79 | IMPDH2 (0.48) | IMPDH2IMPDH1MEN1LMNATHRB | |
| SCHEMBL16968397 | 0.73 | USP8 (0.35) | IMPDH2IMPDH1MEN1LMNATHRB | |
| SCHEMBL10578445 | 0.73 | TDP1 (0.35) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL151936 | 0.72 | IMPDH2 (0.64) | IMPDH2IMPDH1NCOA3MEN1KMT2A | |
| SCHEMBL29489135 | 0.72 | IMPDH2 (0.64) | IMPDH2IMPDH1NCOA3MEN1KMT2A | |
| SCHEMBL1361318 | 0.71 | KDM4E (0.39) | IMPDH2IMPDH1NCOA3MEN1LMNA | |
| SCHEMBL98563 | 0.71 | LMNA (0.55) | IMPDH2IMPDH1MEN1LMNATHRB | |
| SCHEMBL14877095 | 0.71 | MEN1 (0.42) | IMPDH2MEN1LMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592130-B1 | PHOTOCHROMIC MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8748629-B2 | Photochromic material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-06-10 | — | — | US | disclosed |
| EP-2592130-A1 | PHOTOCHROMIC MATERIAL | Mitsubishi Gas Chemical Company, Inc. (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130102775-A1 | PHOTOCHROMIC MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102775-A1 | PHOTOCHROMIC MATERIAL | RB1, BRD4, H1-4 | IMPDH2 4311/4885IMPDH1 3787/4885NCOA3 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.