SCHEMBL14877458

SCHEMBL14877458

c1ccc2cc3cc4c(cc3cc2c1)c1ccccc1c1cc2ccccc2cc14

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
HSD17B10 Q99714 5/20 0.52
HIF1A Q16665 2/20 0.52
CYP1B1 Q16678 1/20 0.52
HPRT1 P00492 3/20 0.50
TDP1 Q9NUW8 2/20 0.48
CYP3A4 P08684 2/20 0.48
ALOX15 P16050 1/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
HBB P68871 1/20 0.48
CYP2A6 P11509 2/20 0.47
TSHR P16473 1/20 0.47
TRPM4 Q8TD43 1/20 0.46
HPGD P15428 3/20 0.46
CYP1A2 P05177 3/20 0.46
THRB P10828 1/20 0.46
HTR2A P28223 1/20 0.44
NQO1 P15559 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711515 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL296990 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL55388 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL29981934 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
Benzo[B]Triphenylene SCHEMBL29628013 0.94 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
Benzo[B]Triphenylene SCHEMBL29374595 0.94 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
Benzo[B]Triphenylene SCHEMBL71635 0.94 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL55215 0.94 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL711725 0.94 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL4855544 0.94 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601701-B2 Organic compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2017-03-21 US claimed
US-20140264312-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2014-09-18 US claimed
US-9601701-B2 Organic compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-9601701-B2 Organic compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-20140264312-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2014-09-18 US disclosed
US-20140264312-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2014-09-18 US disclosed
WO-2013058137-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-04-25 WO disclosed