Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878119 | 0.87 | NR1I2 (0.57) | KEAP1NFE2L2HTTLMNAGAA | |
| SCHEMBL8151104 | 0.84 | F2 (0.42) | KEAP1NFE2L2HTTLMNAGAA | |
| SCHEMBL14878167 | 0.81 | KMT2A (0.61) | HTTLMNAUSP2KMT2AMAPT | |
| SCHEMBL14878181 | 0.81 | F2 (0.67) | F2KAT6AKMT2AMEN1 | |
| SCHEMBL7327551 | 0.76 | ESR1 (0.55) | HTTLMNAGAAUSP2KMT2A | |
| SCHEMBL7328822 | 0.76 | ESR1 (0.54) | KEAP1NFE2L2HTTLMNAGAA | |
| SCHEMBL7335466 | 0.75 | ESR1 (0.59) | KEAP1NFE2L2LMNAKMT2AESR1 | |
| SCHEMBL7333708 | 0.74 | MAPT (0.60) | LMNAMAPTPKM | |
| SCHEMBL7329319 | 0.73 | F2 (0.54) | HTTGAAF2KMT2AMAPT | |
| SCHEMBL7335613 | 0.72 | RAB9A (0.51) | HTTLMNAGAAUSP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426433-B2 | Anticoagulant compounds, pharmaceutical compositions on their basis to treat thrombotic conditions, and plasma-substituting solution to correct hypercoagulation defects of hemodilution | Obschestvo S Ogranichennoi Otvetsttvennoctiyu “Bionika” (RU) | 2013-04-23 | — | — | US | disclosed |