Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878204 | 1.00 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL15304826 | 0.84 | — | — | |
| SCHEMBL6956713 | 0.83 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL6958666 | 0.83 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL6978846 | 0.82 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL6976999 | 0.82 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL14878202 | 0.78 | CHRNB4 (0.35) | — | |
| SCHEMBL14878203 | 0.77 | LTA4H (0.33) | — | |
| SCHEMBL9975285 | 0.77 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL9975260 | 0.77 | IRAK4 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426589-B2 | Process for production of quinazoline derivative | SHIONOGI & CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |