Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014615 | 0.89 | CYP19A1 (0.32) | CYP19A1ALDH1A1GAAUSP2PKM | |
| SCHEMBL14878827 | 0.88 | ALDH1A1 (0.36) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL13523886 | 0.85 | CYP19A1 (0.38) | CYP19A1ALDH1A1GAAUSP2PKM | |
| SCHEMBL13013693 | 0.82 | ALOX15 (0.34) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL13014599 | 0.77 | ALDH1A1 (0.36) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL14878826 | 0.76 | ALDH1A1 (0.33) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL14878835 | 0.75 | ERAP2 (0.30) | — | |
| SCHEMBL6852431 | 0.74 | GAA (0.34) | CYP19A1ALDH1A1GAAUSP2HPGD | |
| SCHEMBL13014888 | 0.72 | KDM4E (0.38) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL14878793 | 0.71 | CYP19A1 (0.38) | CYP19A1MAPTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2584008-B1 | Trisazo acid dyes based on naphtholes | CLARIANT INT LTD (CH) | 2014-06-04 | — | — | EP | disclosed |
| EP-2584007-B1 | Trisazo acid dyes based on pyridones | CLARIANT INT LTD (CH) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013056837-A1 | TRISAZO ACID DYES BASED ON NAPHTHOLES | CLARIANT INTERNATIONAL LTD (CH) | 2013-04-25 | — | — | WO | disclosed |
| WO-2013056839-A1 | TRISAZO ACID DYES BASED ON PYRIDONES | CLARIANT INTERNATIONAL LTD (CH) | 2013-04-25 | — | — | WO | disclosed |
| EP-2584007-A1 | Trisazo acid dyes based on pyridones | Clariant International Ltd. (CH) | 2013-04-24 | — | — | EP | disclosed |
| EP-2584008-A1 | Trisazo acid dyes based on naphtholes | CLARIANT INTERNATIONAL LTD (CH) | 2013-04-24 | — | — | EP | disclosed |