Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15741220 | 0.84 | HSP90AA1 (0.41) | HSP90AA1BIRC5 | |
| SCHEMBL4880774 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP19A1KCNH2BIRC5PTGS1 | |
| SCHEMBL23883491 | 0.79 | KCNH2 (0.42) | ALDH1A1KCNH2 | |
| SCHEMBL30335333 | 0.79 | KCNH2 (0.42) | ALDH1A1KCNH2 | |
| SCHEMBL30234615 | 0.77 | FFAR4 (0.52) | ALDH1A1KCNH2 | |
| SCHEMBL23883999 | 0.77 | FFAR4 (0.52) | ALDH1A1KCNH2 | |
| SCHEMBL1874901 | 0.77 | KCNH2 (0.37) | ALDH1A1CYP19A1KCNH2PTGS2 | |
| SCHEMBL2610313 | 0.74 | KDM4E (0.50) | ALDH1A1 | |
| SCHEMBL122228 | 0.72 | HTR6 (0.52) | ALDH1A1CYP19A1GRM2HSP90AA1 | |
| SCHEMBL17740589 | 0.71 | KDM4E (0.37) | HSP90AA1BIRC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BTK, FLT3, JAK1 | ALDH1A1 3832/4885CYP19A1 1736/4885KCNH2 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.