Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356288 | 0.86 | HSD17B10 (0.36) | ADRA2AADRA1ATSHRHSD17B10MAPT | |
| SCHEMBL100433 | 0.86 | SERPINE1 (0.36) | ADRA2AADRA1ATSHRHSD17B10MAPT | |
| SCHEMBL2485813 | 0.85 | ADRA2A (0.42) | CYP2C19ADRA2AADRA1ATSHRHSD17B10 | |
| SCHEMBL768173 | 0.85 | SERPINE1 (0.31) | — | |
| SCHEMBL56208 | 0.81 | MAPK1 (0.34) | ADRA2AADRA1AACE | |
| SCHEMBL28682094 | 0.81 | TSHR (0.46) | ADRA2AADRA1ATSHRMAPTKMT2A | |
| SCHEMBL1900469 | 0.81 | MAPK1 (0.34) | ADRA2AADRA1AACE | |
| SCHEMBL852013 | 0.81 | DGKA (0.46) | TSHRMAPTKMT2ADGKACYP1A2 | |
| SCHEMBL15007701 | 0.81 | DGKA (0.31) | DGKACYP1A2 | |
| SCHEMBL11554959 | 0.81 | CYP2D6 (0.37) | CYP2C19TSHRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128178-B1 | RESIN COMPOSITION FOR OPTICAL MEMBER AND OPTICAL MEMBER OBTAINED FROM THE SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2013-04-24 | — | — | EP | disclosed |