Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526696 | 0.89 | LMNA (0.52) | MC4RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL753058 | 0.89 | LMNA (0.52) | MC4RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13044393 | 0.82 | LMNA (0.50) | MC4RMAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3637565 | 0.81 | LMNA (0.53) | MC4RMAPTRAB9AMEN1KMT2A | |
| SCHEMBL14277129 | 0.77 | LMNA (0.69) | MEN1KMT2AALDH1A1LMNAOPRM1 | |
| SCHEMBL12103050 | 0.76 | NPY2R (0.53) | MEN1KMT2AALDH1A1LMNAOPRM1 | |
| SCHEMBL12139917 | 0.75 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNAOPRM1 | |
| SCHEMBL6663882 | 0.74 | KMT2A (0.73) | MC4RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3729279 | 0.74 | OPRM1 (0.54) | MEN1KMT2AALDH1A1LMNAOPRM1 | |
| SCHEMBL3729276 | 0.74 | OPRM1 (0.54) | MEN1KMT2AALDH1A1LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242750-B1 | CONFORMATIONALLY RESTRICTED BIPHENYL DERIVATIVES FOR USE AS HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-04-24 | — | — | EP | disclosed |