Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879150 | 0.84 | KDM4E (0.36) | MEN1KMT2ANOTUMALDH1A1KDM4E | |
| SCHEMBL17146135 | 0.79 | MEN1 (0.40) | MEN1KMT2ANOTUMITGB2ICAM1 | |
| SCHEMBL13167842 | 0.79 | MEN1 (0.40) | MEN1KMT2ANOTUMITGB2ICAM1 | |
| SCHEMBL11539893 | 0.77 | NOTUM (0.47) | MEN1KMT2ANOTUMALDH1A1KDM4E | |
| SCHEMBL11539890 | 0.77 | NOTUM (0.47) | MEN1KMT2ANOTUMALDH1A1KDM4E | |
| SCHEMBL20457145 | 0.76 | ITGB2 (0.43) | MEN1KMT2ANOTUMITGB2ICAM1 | |
| SCHEMBL20205837 | 0.76 | ITGB2 (0.43) | MEN1KMT2ANOTUMITGB2ICAM1 | |
| SCHEMBL13130689 | 0.75 | MEN1 (0.37) | MEN1KMT2ANOTUMITGB2ICAM1 | |
| SCHEMBL14879146 | 0.73 | SMN1; SMN2 (0.47) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL803512 | 0.73 | HPGD (0.47) | MEN1KMT2ANOTUMITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164325-B1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO (JP) | 2013-04-24 | — | — | EP | disclosed |