Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 10/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879145 | 0.84 | MEN1 (0.37) | KDM4EALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL6653939 | 0.77 | MIF (0.40) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL6656648 | 0.77 | MIF (0.40) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL18924655 | 0.77 | MIF (0.40) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL20205871 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL13130686 | 0.73 | MAPT (0.35) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL14879146 | 0.72 | SMN1; SMN2 (0.47) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL12609455 | 0.71 | ALDH1A1 (0.44) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL1266177 | 0.71 | RAD52 (0.46) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL16378813 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164325-B1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO (JP) | 2013-04-24 | — | — | EP | disclosed |