Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539890 | 1.00 | NOTUM (0.47) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL12609459 | 0.87 | NOTUM (0.43) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL11540587 | 0.83 | NOTUM (0.40) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL11539391 | 0.83 | NOTUM (0.40) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL11540152 | 0.80 | LMNA (0.41) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL11540155 | 0.80 | LMNA (0.41) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL10313139 | 0.80 | USP9X (0.36) | NOTUMMAPTALDH1A1PLA2G1BATG4B | |
| SCHEMBL433887 | 0.79 | MAPK8 (0.43) | NOTUMLMNAMAPTALDH1A1PLA2G1B | |
| SCHEMBL11540354 | 0.78 | MTNR1A (0.41) | NOTUMLMNAMAPTALDH1A1HPGD | |
| SCHEMBL17146135 | 0.78 | MEN1 (0.40) | NOTUMLMNAMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | claimed |
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | disclosed |