Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.52 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.49 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18803715 | 1.00 | KIF11 (0.52) | KIF11SLC6A11SLC6A1KCNH2CA4 | |
| SCHEMBL18803698 | 0.94 | KIF11 (0.51) | KIF11SLC6A11SLC6A1KCNH2LTA4H | |
| SCHEMBL16197752 | 0.93 | KIF11 (0.50) | KIF11SLC6A11SLC6A1KCNH2CA4 | |
| SCHEMBL18413416 | 0.89 | KIF11 (0.47) | KIF11SLC6A11SLC6A1KCNH2LTA4H | |
| SCHEMBL5819943 | 0.89 | KIF11 (0.47) | KIF11SLC6A11SLC6A1KCNH2LTA4H | |
| SCHEMBL5819858 | 0.89 | KIF11 (0.47) | KIF11SLC6A11SLC6A1KCNH2LTA4H | |
| SCHEMBL21574354 | 0.88 | SLC6A11 (0.46) | KIF11SLC6A11SLC6A1KCNH2LTA4H | |
| SCHEMBL20644235 | 0.87 | KIF11 (0.50) | KIF11SLC6A11SLC6A1KCNH2CA4 | |
| SCHEMBL13003134 | 0.87 | KIF11 (0.50) | KIF11SLC6A11SLC6A1KCNH2CA4 | |
| SCHEMBL2348691 | 0.87 | KIF11 (0.65) | KIF11SLC6A1KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064223-B1 | Duplex oligonucleotide complexes and methods for gene silencing by RNA interference | DHARMACON INC (US) | 2013-04-24 | — | — | EP | disclosed |