Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879595 | 0.86 | GPBAR1 (0.31) | GPBAR1 | |
| SCHEMBL14879547 | 0.83 | — | — | |
| SCHEMBL14879419 | 0.83 | — | — | |
| SCHEMBL14879456 | 0.82 | — | — | |
| SCHEMBL14879689 | 0.81 | — | — | |
| SCHEMBL14879754 | 0.81 | — | — | |
| SCHEMBL14879450 | 0.80 | P2RX7 (0.32) | — | |
| SCHEMBL14879652 | 0.79 | — | — | |
| SCHEMBL14879517 | 0.79 | — | — | |
| SCHEMBL16009552 | 0.72 | RAB9A (0.35) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768810-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013059666-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-04-25 | — | — | WO | disclosed |