Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.76 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883 | 0.88 | CA12 (0.65) | NFE2L2NQO2ALDH1A1CYP2A6RELA | |
| SCHEMBL5495422 | 0.86 | NFE2L2 (1.00) | NFE2L2NQO2ALDH1A1RELALMNA | |
| SCHEMBL5495425 | 0.86 | NFE2L2 (1.00) | NFE2L2NQO2ALDH1A1RELALMNA | |
| SCHEMBL7024215 | 0.85 | — | — | |
| SCHEMBL8298 | 0.85 | — | — | |
| Water SCHEMBL28134264 | 0.83 | NFE2L2 (0.70) | NFE2L2NQO2ALDH1A1CYP3A4KDM4E | |
| SCHEMBL7792584 | 0.81 | NFE2L2 (0.68) | NFE2L2NQO2RELA | |
| SCHEMBL7792580 | 0.81 | NFE2L2 (0.68) | NFE2L2NQO2RELA | |
| SCHEMBL18240773 | 0.81 | NFE2L2 (0.75) | NFE2L2NQO2RELAKDM4EMAOB | |
| SCHEMBL18240792 | 0.81 | NFE2L2 (0.75) | NFE2L2ALDH1A1RELATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906970-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS WITH REDUCED TACK | NOVARTIS AG (CH) | 2016-11-23 | — | — | EP | claimed |
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |