Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257736 | 0.86 | AKR1B10 (0.48) | POLBGAAALOX5KMT2AMEN1 | |
| SCHEMBL29794297 | 0.84 | CYP2D6 (0.51) | POLBGAAL3MBTL1NPSR1HTT | |
| SCHEMBL467919 | 0.84 | CYP2D6 (0.51) | POLBGAAL3MBTL1NPSR1HTT | |
| SCHEMBL27885698 | 0.83 | POLB (0.49) | TAAR1POLBL3MBTL1NPSR1HTT | |
| SCHEMBL28936427 | 0.83 | MMP2 (0.56) | POLBL3MBTL1NPSR1HTTHPGD | |
| SCHEMBL10523437 | 0.81 | TSHR (0.45) | POLBGAAHTTHPGDKMT2A | |
| SCHEMBL29889833 | 0.80 | POLB (0.53) | POLBL3MBTL1NPSR1HTTKMT2A | |
| SCHEMBL24977468 | 0.80 | POLB (0.53) | POLBL3MBTL1NPSR1HTTKMT2A | |
| SCHEMBL1999919 | 0.80 | POLB (0.53) | POLBL3MBTL1NPSR1HTTKMT2A | |
| SCHEMBL27436626 | 0.80 | POLB (0.53) | POLBL3MBTL1NPSR1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768873-A2 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013057026-A2 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2013-04-25 | — | — | WO | disclosed |