Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.54 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870756 | 0.85 | TAS1R3 (0.59) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL679553 | 0.85 | KAT6A (0.58) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31180472 | 0.85 | KAT6A (0.58) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18525797 | 0.85 | TAS1R3 (0.59) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27971451 | 0.85 | KAT6A (0.58) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL30978290 | 0.84 | KAT6A (0.56) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13753373 | 0.83 | NPSR1 (0.64) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13701706 | 0.83 | TAS1R3 (0.56) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6748367 | 0.83 | KAT6A (0.55) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30184372 | 0.83 | TAS1R3 (0.56) | HDAC8KAT6ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |