Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.59 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.58 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870756 | 1.00 | TAS1R3 (0.59) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL14881985 | 0.85 | HDAC8 (0.64) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL30184372 | 0.84 | TAS1R3 (0.56) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL13753373 | 0.84 | NPSR1 (0.64) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL13701706 | 0.84 | TAS1R3 (0.56) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL31180472 | 0.84 | KAT6A (0.58) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL27971451 | 0.84 | KAT6A (0.58) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL679553 | 0.84 | KAT6A (0.58) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL7055657 | 0.83 | MRGPRX4 (0.63) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 | |
| SCHEMBL13702288 | 0.83 | GPR139 (0.60) | TAS1R3TAS1R1TAS1R2KAT6AGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11576924-B2 | Compounds for the prevention and treatment of diseases and the use thereof | GALECTIN SCIENCES, LLC (US) | 2023-02-14 | — | — | US | disclosed |
| EP-3487840-B1 | CYCLOHEXYL BENZAMIDE COMPOUNDS | LILLY CO ELI (US) | 2021-08-11 | — | — | EP | disclosed |
| US-9783522-B2 | 2-amino-pyridine and 2-amino-pyrimidine derivatives and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| CN-106478497-A | Aryl amine derivatives as TTX S blocker | 拉夸里亚创药株式会社 | 2017-03-08 | — | — | CN | disclosed |
| US-20170044133-A1 | NOVEL 2-AMINO-PYRIDINE AND 2-AMINO-PYRIMIDINE DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |
| CN-103249721-B | Arylamine Derivatives as TTX-S Blockers | 拉夸里亚创药株式会社 | 2016-10-12 | — | — | CN | disclosed |
| CN-104822666-B | Terazololine-one compound and application thereof | 住友化学株式会社 | 2016-09-21 | — | — | CN | disclosed |
| CN-104822666-A | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL CO | 2015-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044133-A1 | NOVEL 2-AMINO-PYRIDINE AND 2-AMINO-PYRIMIDINE DERIVATIVES AND MEDICINAL USE THEREOF | ENPP2, ATXN2, ATXN2L | TAS1R3 3704/4885TAS1R1 3571/4885TAS1R2 3065/4885 |
| US-11576924-B2 | Compounds for the prevention and treatment of diseases and the use thereof | LGALS1, LGALS3BP, LGALS2 | TAS1R3 1535/4885TAS1R1 1645/4885TAS1R2 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.