Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369949 | 0.82 | CA2 (0.41) | MAPTKMT2AALDH1A1POLBCA12 | |
| SCHEMBL1477422 | 0.82 | POLB (0.39) | MAPTKMT2AALDH1A1POLBCA12 | |
| SCHEMBL26964200 | 0.82 | KMT2A (0.35) | MAPTKMT2AALDH1A1POLBCA12 | |
| SCHEMBL27996705 | 0.81 | POLB (0.38) | MAPTKMT2AALDH1A1POLBCA12 | |
| SCHEMBL11739171 | 0.80 | CA12 (0.34) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL19881529 | 0.79 | TLR8 (0.54) | MAPTKMT2AALDH1A1POLBCA12 | |
| SCHEMBL569047 | 0.78 | JMJD6 (0.32) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL11738816 | 0.78 | SMN1; SMN2 (0.40) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24533248 | 0.77 | CA12 (0.43) | KMT2AALDH1A1POLBCA12CA1 | |
| SCHEMBL9986639 | 0.77 | KDM4E (0.38) | MAPTKMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160130454-A1 | INK COMPOSITION | SEIKO EPSON CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| EP-2723738-A1 | CRYSTAL OF FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-04-30 | — | — | EP | disclosed |
| EP-2585462-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2013-05-01 | — | — | EP | disclosed |