Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986639 | 0.81 | KDM4E (0.38) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL14889017 | 0.78 | MAPT (0.37) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL11738816 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3589853 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL568442 | 0.71 | KMT2A (0.36) | CA12CA1CA2CA9 | |
| SCHEMBL24533248 | 0.71 | CA12 (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL11739171 | 0.71 | CA12 (0.34) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL14889035 | 0.70 | DGAT1 (0.34) | — | |
| SCHEMBL19881529 | 0.70 | TLR8 (0.54) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL662371 | 0.70 | LMNA (0.38) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601192-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012018909-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-09 | — | — | WO | disclosed |