Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561154 | 0.81 | L3MBTL1 (0.50) | MCHR1KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL31662197 | 0.79 | MCHR1 (0.47) | MCHR1KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL1728493 | 0.78 | MCHR1 (0.78) | MCHR1KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL14408275 | 0.77 | MCHR1 (0.62) | MCHR1KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9950840 | 0.73 | NPC1 (0.51) | NPC1RAB9AL3MBTL1SMN1; SMN2PKM | |
| SCHEMBL4667910 | 0.72 | L3MBTL1 (0.53) | MCHR1KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL4484736 | 0.71 | MAPK14 (0.76) | MCHR1KCNH2 | |
| SCHEMBL10059366 | 0.71 | KDM4E (0.62) | MCHR1KCNH2NPC1RAB9AL3MBTL1 | |
| SCHEMBL27367676 | 0.70 | LMNA (0.82) | RAB9AL3MBTL1SMN1; SMN2MAOBGSTP1 | |
| SCHEMBL339813 | 0.70 | LMNA (0.82) | RAB9AL3MBTL1SMN1; SMN2MAOBGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585462-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2013-05-01 | — | — | EP | disclosed |