Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889962 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14889632 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14889629 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14760269 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14760268 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14890021 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14889754 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14889959 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14900550 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 | |
| SCHEMBL14890022 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567951-B1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-09-19 | — | — | EP | disclosed |
| EP-3301086-A1 | PRODUCTION OF A COMPOSITION CONTAINING A COMPLEX BETWEEN A MEMBRANE COMPOSED OF A LIPID MONOLAYER AND A NUCLEIC ACID, AND, A LIPID MEMBRANE FOR ENCAPSULATING THE COMPLEX THEREIN | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9920028-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |
| US-9845306-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-19 | — | — | US | disclosed |
| US-20170349532-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20160304487-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-10-20 | — | — | US | disclosed |
| US-9408914-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-08-09 | — | — | US | disclosed |
| US-20150343062-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2774912-A1 | CATIONIC LIPID | Kyowa Hakko Kirin Co., Ltd. (JP) | 2014-09-10 | — | — | EP | disclosed |
| US-20130280305-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20130108685-A1 | CATIONIC LIPID | KYOWA KIRIN CO., LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304487-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | S1PR5 1206/4885S1PR1 520/4885S1PR3 247/4885 |
| US-20170349532-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | S1PR5 1206/4885S1PR1 520/4885S1PR3 247/4885 |
| US-20130108685-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | S1PR5 1206/4885S1PR1 520/4885S1PR3 247/4885 |
| US-20130280305-A1 | CATIONIC LIPID | LPAR3, ACOX3, H1-3 | S1PR5 1206/4885S1PR1 520/4885S1PR3 247/4885 |
| US-20150343062-A1 | CATIONIC LIPID | ACOX3, LPAR3, ELOVL3 | S1PR5 1310/4885S1PR1 505/4885S1PR3 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.