SCHEMBL14890

SCHEMBL14890

C=Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
NPFFR2 Q9Y5X5 2/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CHAT P28329 1/20 0.44
TP53 P04637 2/20 0.43
AHR P35869 1/20 0.43
PYGL P06737 3/20 0.40
TSHR P16473 2/20 0.40
CYP3A4 P08684 1/20 0.40
HSD17B10 Q99714 1/20 0.40
IGF1R P08069 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
KDM4A O75164 1/20 0.39
KDM4B O94953 1/20 0.39
NPC1 O15118 1/20 0.39
THRB P10828 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
G6PC1 P35575 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30620702 1.00 ALDH1A1 (0.58) ALDH1A1NPFFR2KMT2ANPSR1CHAT
Formic Acid SCHEMBL27776658 0.89 ALDH1A1 (0.59) ALDH1A1NPFFR2KMT2ANPSR1CHAT
SCHEMBL28732535 0.84 ALDH1A1 (0.67) ALDH1A1NPFFR2KMT2ANPSR1CHAT
SCHEMBL28732534 0.81 ALDH1A1 (0.43) ALDH1A1CHATTP53TSHRCYP3A4
SCHEMBL22964718 0.80 ALDH1A1 (0.50) ALDH1A1NPSR1TP53TSHRTDP1
SCHEMBL2439383 0.80 ALDH1A1 (0.50) ALDH1A1NPSR1TP53TSHRTDP1
SCHEMBL4902284 0.78 ALDH1A1 (0.43) ALDH1A1CHATTP53TSHRTDP1
SCHEMBL1122511 0.78 CYP3A4 (0.46) ALDH1A1NPSR1TP53CYP3A4TDP1
SCHEMBL578860 0.78 TDP1 (0.45) ALDH1A1KMT2ANPSR1CHATTP53
SCHEMBL16953710 0.78 ALDH1A1 (0.43) ALDH1A1KMT2ATP53AHRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3524 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112987519-B Toner and two-component developer 佳能株式会社 2024-12-27 CN claimed
CN-119039522-A ASA resin and preparation method thereof 中化学科学技术研究有限公司 2024-11-29 CN claimed
CN-118459684-A Impact modifier, preparation method and modified resin 中化学科学技术研究有限公司 2024-08-09 CN claimed
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
CN-115368523-B Multi-block thermoplastic elastomer and preparation method thereof 安徽农业大学 2024-03-19 CN claimed
US-11835873-B2 Toner and two component developer CANON KABUSHIKI KAISHA (JP) 2023-12-05 US claimed
WO-2023049779-A1 AN AQUEOUS COATING COMPOSITION AND A PACKAGE COATED THEREWITH PPG INDUSTRIES OHIO, INC. (US) 2023-03-30 WO claimed
CN-115368523-A Multi-block thermoplastic elastomer and preparation method thereof 安徽农业大学 2022-11-22 CN claimed
WO-2022169971-A1 AN AQUEOUS COATING COMPOSITION AND A PACKAGE COATED THEREWITH PPG INDUSTRIES OHIO, INC. (US) 2022-08-11 WO claimed
CN-114375355-A Non-solvent 2K polyurethane artificial leather composition, artificial leather prepared from same and preparation method of artificial leather 陶氏环球技术有限责任公司 2022-04-19 CN claimed
US-4617329-A POLYESTER OR POLYCARBONATE AND MULTISTAGE STYRENIC POLYMER ROHM AND HAAS COMPANY (US) 1986-10-14 US claimed
US-4587203-A USING A DEVELOPMENT SOLVENT AND RINSING NONSOLVENT; SILANE COUPLING INTERLAYER; DIMENSIONAL STABILITY AND SHARPNESS OF IMAGE HUGHES AIRCRAFT COMPANY (US) 1986-05-06 US claimed
EP-0174207-A2 Preparation of poly(arylene ether ketones) RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-03-12 EP claimed
US-4557994-A MICROPATTERN OF TERPOLYMER RESISTANT TO RUBBING AND PRESSURE FUJI PHOTO FILM CO., LTD. (JP) 1985-12-10 US claimed
US-4557991-A BINDER RESIN, WAX AND COLORANT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-12-10 US claimed
US-4535054-A IRRADIATION TO GIVE NEGATIVE PATTERN IMAGE, DEVELOPMENT BY DISSOLUING UNEXPOSED POLYMER WITH SOLVENT AND RINSING HUGHES AIRCRAFT COMPANY (US) 1985-08-13 US claimed
EP-0132339-A2 Pigmented thermoplastic resin compositions ROHM AND HAAS COMPANY (US) 1985-01-30 EP claimed
EP-0030716-B1 CHLORINATED PVC BLENDS WITH IMPROVED PROCESSABILITY The B.F. GOODRICH Company (US) 1984-02-08 EP claimed
US-4415644-A PARTICLES FORMED BY SUSPENSION POLYMERIZATION IN THE PRESENCE OF A DEMULSIFIER; HIGH DENSITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-11-15 US claimed
EP-0092794-A2 Light-sensitive printing plate FUJI PHOTO FILM CO., LTD. (JP) 1983-11-02 EP claimed