SCHEMBL4902284

SCHEMBL4902284

C=Cc1ccc(Cl)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
TP53 P04637 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAOB P27338 1/20 0.35
TRPA1 O75762 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34
KCNA3 P22001 1/20 0.34
TSHR P16473 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
KMO O15229 1/20 0.33
SLC6A3 Q01959 1/20 0.33
NFE2L2 Q16236 3/20 0.32
CHAT P28329 1/20 0.32
MAPT P10636 3/20 0.32
LMNA P02545 1/20 0.32
DYRK1A Q13627 1/20 0.31
MAPK1 P28482 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12826297 0.86 KCNA3 (0.39) KCNA3KMO
SCHEMBL765941 0.82 ALDH1A1 (0.43) ALDH1A1TP53TDP1MAOBTRPA1
SCHEMBL2095564 0.78 NFE2L2 (0.38) ALDH1A1MAOBRAPGEF4KCNA3SLC6A3
SCHEMBL2095566 0.78 NFE2L2 (0.38) ALDH1A1MAOBRAPGEF4KCNA3SLC6A3
SCHEMBL29662132 0.78 NFE2L2 (0.50) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL14890 0.78 ALDH1A1 (0.58) ALDH1A1TP53TDP1TSHRCHAT
SCHEMBL248639 0.78 NFE2L2 (0.50) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL30620702 0.78 ALDH1A1 (0.58) ALDH1A1TP53TDP1TSHRCHAT
SCHEMBL16955558 0.77 KCNA3 (0.37) ALDH1A1MAOBTRPA1RAPGEF4KCNA3
SCHEMBL20861086 0.77 ALDH1A1 (0.37) ALDH1A1MAOBRAPGEF4KCNA3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251696-B1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2024-11-20 EP disclosed
EP-4127039-B1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS STYROLUTION GROUP GMBH (DE) 2024-11-20 EP disclosed
US-20240317968-A1 HIGH CLARITY AND LOW HAZE UV STABILIZED STYRENE AND METHYL METHACRYLATE COPOLYMERS INEOS STYROLUTION GROUP GMBH (DE) 2024-09-26 US disclosed
US-20240010825-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2024-01-11 US disclosed
EP-4251696-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS Styrolution Group GmbH (DE) 2023-10-04 EP disclosed
US-20230183404-A1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS STYROLUTION GROUP GMBH (DE) 2023-06-15 US disclosed
US-11661397-B2 1,4-disubstituted imidazole derivative Sumitomo Pharma Co., Ltd. (JP) 2023-05-30 US disclosed
WO-2023041512-A1 HIGH CLARITY AND LOW HAZE UV STABILIZED STYRENE AND METHYL METHACRYLATE COPOLYMERS INEOS STYROLUTION GROUP GMBH (DE) 2023-03-23 WO disclosed
EP-4127039-A1 HIGH DARKNESS AND HIGH GLOSS DIMENSIONALLY STABLE THERMOPLASTIC SMMA MOLDING COMPOSITION INEOS Styrolution Group GmbH (DE) 2023-02-08 EP disclosed
WO-2022112590-A1 UV RESISTANT SMMA COPOLYMERS WITH LOW HAZE AND HIGH CLARITY INEOS STYROLUTION GROUP GMBH (DE) 2022-06-02 WO disclosed
US-4035275-A ELECTRODEPOSITION, CATIONIC EPOXY RESINS PPG INDUSTRIES, INC. (US) 1977-07-12 US disclosed
US-4031290-A ALPHA-BETA MONOMERS, CATALYSIS PPG INDUSTRIES, INC. (US) 1977-06-21 US disclosed
US-4016332-A OF ETHYLENICALLY UNSATURATED MONOMERS PPG INDUSTRIES, INC. (US) 1977-04-05 US disclosed
US-4001156-A Method of producing epoxy group-containing, quaternary ammonium salt-containing resins PPG INDUSTRIES, INC. (US) 1977-01-04 US disclosed
US-3975346-A ELECTRO-DEPOSITION PPG INDUSTRIES, INC. (US) 1976-08-17 US disclosed
US-3959106-A EPOXY COMPOUNDS; SULFIDES PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed
US-3939051-A Process for electrodeposition of cationic thermosetting compositions PPG INDUSTRIES, INC. (US) 1976-02-17 US disclosed
US-3937679-A COATINGS, AMMONIUM, SULFONIUM, OR PHOSPHONIUM ACID SALT, AMINE-ALDEHYDE CONDENSATE, AND A METHYOL PHENOL ETHER PPG INDUSTRIES, INC. (US) 1976-02-10 US disclosed
US-3936405-A CATIONIC POLYMER PPG INDUSTRIES, INC. (US) 1976-02-03 US disclosed
US-3933940-A Mercaptan blocked thermosetting copolymers PPG INDUSTRIES, INC. (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661397-B2 1,4-disubstituted imidazole derivative NR4A3, NR0B1, NR2C2 ALDH1A1 278/4885TP53 247/4885TDP1 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.