Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28531625 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL14890155 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL1678150 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2TSHRL3MBTL1ATMTDP1 | |
| Hydrochloric Acid SCHEMBL327083 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2TSHRL3MBTL1ATMTDP1 | |
| Iodide SCHEMBL3466446 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2TSHRL3MBTL1ATMTDP1 | |
| Bromide SCHEMBL3466620 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL14890478 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRL3MBTL1ATMHTT | |
| SCHEMBL19307323 | 0.76 | MEN1 (0.30) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9828090 | 0.75 | CA2 (0.53) | SMN1; SMN2ATMTDP1HTTMEN1 | |
| SCHEMBL17078160 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRL3MBTL1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908959-B2 | Polyacrylamide resin, papermaking additive, and paper | HARIMA CHEMICALS, INCORPORATED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20170253683-A1 | POLYACRYLAMIDE RESIN, PAPERMAKING ADDITIVE, AND PAPER | HARIMA CHEMICALS, INCORPORATED (JP) | 2017-09-07 | — | — | US | disclosed |
| US-20150211130-A1 | ANTI-CORROSIVE AGENT FOR WASHING OF METAL WITH ACID, DETERGENT SOLUTION COMPOSITION, AND METHOD FOR WASHING OF METAL | NITTO BOSEKI CO LTD (JP) | 2015-07-30 | — | — | US | disclosed |
| US-20130109607-A1 | ANTI-CORROSIVE AGENT FOR WASHING OF METAL WITH ACID, DETERGENT SOLUTION COMPOSITION, AND METHOD FOR WASHING OF METAL | NITTO BOSEKI CO., LTD. (JP) | 2013-05-02 | — | — | US | disclosed |