Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224959 | 0.83 | NAAA (0.40) | NAAA | |
| SCHEMBL6164386 | 0.79 | NAAA (0.38) | NAAA | |
| SCHEMBL10653192 | 0.78 | NAAA (0.37) | NAAA | |
| SCHEMBL10203044 | 0.73 | AAK1 (0.36) | NAAA | |
| SCHEMBL22572291 | 0.71 | CYP1A2 (0.39) | NAAA | |
| SCHEMBL29104167 | 0.70 | NAAA (0.48) | NAAA | |
| SCHEMBL1108475 | 0.70 | NAAA (0.44) | NAAA | |
| SCHEMBL19114235 | 0.70 | NAAA (0.35) | NAAA | |
| SCHEMBL19540309 | 0.70 | NAAA (0.32) | NAAA | |
| SCHEMBL87389 | 0.69 | NAAA (0.47) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187450-B2 | Substituted pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-2592076-B1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-05-13 | — | — | EP | disclosed |
| US-20140213549-A9 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20140005143-A2 | Substituted PyridineCompound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2592076-A1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109653-A1 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213549-A9 | Substituted Pyridine Compound | CETP, MTTP, PRCP | NAAA 80/4885 |
| US-20140005143-A2 | Substituted PyridineCompound | CETP, MTTP, CES1 | NAAA 231/4885 |
| US-20130109653-A1 | Substituted Pyridine Compound | CETP, MTTP, PRCP | NAAA 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.