Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448272 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL14305750 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| Water SCHEMBL28195092 | 0.98 | NAAA (0.46) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL9819021 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL483412 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL7524061 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL9009688 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| Hydrogen Sulfide SCHEMBL28858234 | 0.98 | NAAA (0.46) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL15225261 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 | |
| SCHEMBL3233378 | 0.98 | NAAA (0.50) | NAAATDP1L3MBTL1KCNH2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 745 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240154-A1 | COLONIC ORGANOIDS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-18 | — | — | US | claimed |
| CN-117080510-A | Proton exchange membrane for fuel cell and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-11-17 | — | — | CN | claimed |
| WO-2023196235-A1 | METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES | GLAZIER ALAN NEIL (US) | 2023-10-12 | — | — | WO | claimed |
| US-20230310471-A1 | METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES | GLAZIER ALAN NEIL (US) | 2023-10-05 | — | — | US | claimed |
| US-11767515-B2 | Colonic organoids and methods of making and using same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-09-26 | — | — | US | claimed |
| US-20230147744-A1 | METHODS TO ENRICH ENTEROENDOCRINE CELLS AND THEIR SUBTYPES IN THE CONTIGUOUS, INTESTINAL MONOLAYER SYSTEMS | UNIVERSITY OF WASHINGTON | 2023-05-11 | — | — | US | claimed |
| EP-4126218-A1 | METHODS TO ENRICH ENTEROENDOCRINE CELLS AND THEIR SUBTYPES IN THE CONTIGUOUS, INTESTINAL MONOLAYER SYSTEMS | The University of North Carolina at Chapel Hill (US) | 2023-02-08 | — | — | EP | claimed |
| CN-115677588-A | 2,3,5,5-tetrasubstituted-4-carbonyl imidazole cyclic nitrone compound, preparation method and application | 中国科学院成都有机化学有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-111362880-B | Synthesis method of alkyl and aryl-containing pyrimidine compound | 新乡医学院（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | claimed |
| WO-2004015025-A1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | claimed |
| EP-1364419-A2 | POLYMERS HAVING ATTACHED LUMINESCENT METAL COMPLEXES AND DEVICES MADE WITH SUCH POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-11-26 | — | — | EP | claimed |
| US-20030148142-A1 | Polymers having attached luminescent metal complexes and devices made with such polymers | LG CHEM, LTD. (KR) | 2003-08-07 | — | — | US | claimed |
| WO-2002102796-A1 | STEREOSELECTIVE METHOD FOR THE PREPARATION OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2002-12-27 | — | — | WO | claimed |
| WO-2002031896-A2 | POLYMERS HAVING ATTACHED LUMINESCENT METAL COMPLEXES AND DEVICES MADE WITH SUCH POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-18 | — | — | WO | claimed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | claimed |
| CN-1230943-A | Process for the preparation of aryl-beta-diketones, aryl-pyrimidinones and crop protection intermediates | ZENECA LTD (GB) | 1999-10-06 | — | — | CN | claimed |
| EP-0694526-B1 | Process for preparation of fluorinated beta-keto ester | ROHM & HAAS (US) | 1998-10-07 | — | — | EP | claimed |
| US-5493025-A | Process for preparation of fluorinated beta-keto ester | ROHM AND HAAS COMPANY (US) | 1996-02-20 | — | — | US | claimed |
| EP-0694526-A1 | Process for preparation of fluorinated beta-keto ester | ROHM AND HAAS COMPANY (US) | 1996-01-31 | — | — | EP | claimed |