Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759433 | 0.98 | DRD2 (0.44) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL27729120 | 0.93 | DRD2 (0.41) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL9341092 | 0.89 | DRD2 (0.43) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL8194487 | 0.89 | DRD2 (0.51) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL5040660 | 0.89 | KDM1A (0.46) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL20790196 | 0.84 | KDM1A (0.48) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL31367100 | 0.81 | KDM1A (0.46) | DRD2ALOX15ALOX12KDM1AMAOA | |
| SCHEMBL27997337 | 0.80 | HTR2C (0.58) | DRD2ADRA1A | |
| SCHEMBL16979032 | 0.79 | PRMT5 (0.38) | ALOX15ALOX12ALDH1A1SMN1; SMN2KCNH2 | |
| SCHEMBL20408758 | 0.79 | PRMT5 (0.38) | ALOX15ALOX12ALDH1A1SMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-107849049-A | Urea derivatives or pharmaceutically acceptable salts thereof | 杏林制药株式会社 | 2018-03-27 | — | — | CN | disclosed |
| WO-2013062966-A2 | NOVEL TRPV3 MODULATORS | ABBVIE INC. (US) | 2013-05-02 | — | — | WO | disclosed |