Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760745 | 0.87 | CHRM1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4551049 | 0.86 | GPR84 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL4551050 | 0.86 | GPR84 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5324661 | 0.86 | CHRM1 (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5324656 | 0.86 | CHRM1 (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL1168493 | 0.83 | SLC7A5 (0.42) | TDP1SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL1168496 | 0.83 | SLC7A5 (0.42) | TDP1SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL7055852 | 0.83 | CHRM1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL22228590 | 0.82 | TDP1 (0.46) | TDP1SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL1578974 | 0.82 | TDP1 (0.46) | TDP1SLC1A2SLC1A1SLC1A3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140272066-A1 | GLUTAMIC ACID DERIVATIVES | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20140272066-A1 | GLUTAMIC ACID DERIVATIVES | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20140272066-A1 | GLUTAMIC ACID DERIVATIVES | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| EP-2770845-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013060814-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-02 | — | — | WO | disclosed |