Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7059468 | 0.98 | CHRM1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL7053586 | 0.98 | CHRM1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL6760745 | 0.91 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL4774070 | 0.87 | CA2 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL27637001 | 0.87 | CA2 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL29634861 | 0.87 | CA2 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1168875 | 0.85 | SLC7A5 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL755924 | 0.85 | SLC7A5 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL7420375 | 0.85 | SLC7A5 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28319949 | 0.83 | SLC7A5 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| US-20030229145-A1 | Pain treatment methods and compositions | GRUENENTHAL GMBH (DE) | 2003-12-11 | — | — | US | claimed |
| EP-1326826-A1 | USE OF AMINO ACIDS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2003-07-16 | — | — | EP | claimed |
| WO-2002030871-A1 | USE OF AMINO ACIDS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | claimed |
| US-20150196895-A1 | CO2 SORPTION BY SUPPORTED AMINO ACID IONIC LIQUIDS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2015-07-16 | — | — | US | disclosed |
| US-20150196895-A1 | CO2 SORPTION BY SUPPORTED AMINO ACID IONIC LIQUIDS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2015-07-16 | — | — | US | disclosed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |
| US-20030229145-A1 | Pain treatment methods and compositions | GRUENENTHAL GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1326826-A1 | USE OF AMINO ACIDS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030871-A1 | USE OF AMINO ACIDS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229145-A1 | Pain treatment methods and compositions | AADAT, BCAT2, BCAT1 | CHRM1 3602/4885AKR1A1 4191/4885CHRM3 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.